A Definite Difference of Opinions Essays - Free Essays, Term Papers

A Definite Difference of Opinions During the development of the young country of the United States of America, everyone had the ability to include their opinions on any subject. But many times, only a few voices were actually listened to. In this case Thomas Jefferson, a Republican, and Alexander Hamilton, a Federalist, were two of the most prominent people in the production of this government. Although disagreement was very common with these two, their contradictions definitely attributed to the development of America. During the first term of presidency Alexander Hamilton had the advantage over Jefferson since he was a great ally with the president George Washington. At this time Hamilton was chosen as the Secretary of Treasury, which was an important job. Hamilton created financial plans that would supposedly clear the debt of the United States. During one situation, Hamilton produced a deal with Jefferson and his Republican friends that moved the nations capitol to Philadelphia. But that was one of the very few agreements between the two. One very popular debate occurred soon after the nations capitol moved. It is referred to as the debate between a "broad" and a "strict" construction of the new Constitution. Hamilton came up with a bank proposal that would produce banks around the country. Hamiltons idea was to keep the current of commerce flowing, and to keep business leaders happy by building a bank capitol. Thomas Jefferson was in great opposition to this idea. He and his friends explained that they did not want a country fill with cities, mills, mines, and factories; they would much rather see the farming production prosper in this country. Jefferson and his colleagues had bent their ideas with the national and state debts, but in no way would they receive the bank proposal lying down. They complained that the Constitution did not give Congress power to build banks; therefore, they should not be permitted. Hamilton, on the hand, explained that the Constitution stated that the government would pr! oduce a proper way of managing money, which the bank was for. George Washington believed arguments by both Hamilton and Jefferson, but he decided to sign the bill. As a result, economy was greatly affected in Americas development. Another great disagreement between the two was the whole idea of foreign affairs. The Federalists, led by Hamilton, supposedly believed that they should have never broken from the great empire. In times of war they repeatedly showed favoritism to Great Britain, the supposed enemies. The Republicans, led by Jefferson and Madison, favored the country of France and the common citizens of the country. They influenced the common people of France to overthrow the French Nobility. A third difference of opinion centered around life styles of the American people. Basically Jefferson despised the idea of a New York City kind of country, he believed it would bring crime and other consequences. Jefferson wanted a more of a Wisconsin type of country, where everyone owned their own land and had their own type of freedom. Hamilton and the Federalists had totally different beliefs, wanting cities and factories in the country. After the election of John Adams in 1796 differences between the ideas of Jefferson and Hamilton grew larger. The acts produced by the Federalist party deeply troubled Jefferson and the Republicans. Although a little harsh, the Alien and Sedition Acts in 1798, produced a way for the Federalists to revolt against Republican opposition and to increase power for themselves. These acts did not permit anyone to criticize the government at all, through writing, or any other way. It also extended the time to become an American citizen, since the Federalists believed that most of the foreigners would become Republicans. This deeply troubled Jefferson and Madison, but they had to find a way to fight back for the Republicans. Jefferson reacted with the production of the Kentucky Resolutions, which permitted states the power to judge a bill or law, unconstitutional, or invalid. This allowed the states to control the laws that would circulate their area. This, and other reactions ! by the Republicans contradicted the acts produced by the Federalists and almost equalized power on both sides. As you can see, Alexander Hamilton and Thomas Jefferson argued about many subjects to

Molecular Biology Essay Example | Topics and Well Written Essays - 2000 words

Molecular Biology - Essay Example For monoclonal antibody, mice are immunised with purified protein. Mouse splenocytes are collected after the immunisation process and fused with myeloma cells. To obtain monoclonal antibodies individual B cells are fused to myeloma cells and isolated by serial dilution resulting to a fusion product or hybridoma cell line of which can produce one specific antibody for extended periods of time by tissue culture. These hybridomas can be screened and best clones cultured in standard tissue culture facilities. The hybridoma cell line obtained for a given antibody was injected into the peritoneal cavity of mice where it grew and simultaneously produces the antibodies. Ascetic fluid containing the antibodies was harvested from the peritoneal cavity after a period of time. One fusion may produce 1000hybridomas therefore one must choose the most appropriate. This might be the highest infinity mAb but could be the most stable, the least cross reacting, the highest specificity depending on what is required. The advantage of using monoclonal antibodies is that they are monospecific, they tend to reduce cross reactivity and useful in diagnostics such as tissue typing. They are highly reproducible, can use relatively impure antigens to immunise animas, theoretically have limitless supply and can manufacture using recombinant DNA technology plus phage display libraries to produce fully human antibodies of any specificity. Labelling antibodies is useful as it enables detection of antibodies. Currently, the most commonly used are fluorescent labels, enzyme labels, chemiluminescent labels and radioactive labels. These are sometimes amplified using Avidin-Biotin Conjugate system. Some common fluorescent labels include, Fluorescein isothiocyanate, DAPI, Phycoerithrin and Texas red. When using enzyme labels, an enzyme is covalently attached to the

The five functions of management Essay Example | Topics and Well Written Essays - 1000 words

The five functions of management - Essay Example The five functions of management This function enables the managers to distribute authority to individual job holders or other employees (Martin and Fellenz 1-75). Controlling can be seen as a four step process of establishing performance standards based on the company’s mission and objectives, measuring and reporting of actual performance, comparing the two and taking of other corrective or preventive actions that may be deemed necessary to solve a particular problem. The main purpose of controlling is to identify deviations from the objectives and taking corrective action (French, Rayner and Rees 12-25). Directing refers to the ability to influence people’s behavior through the motivation, communication, group dynamics, leadership and discipline. The aim of directing is to channel the behavior of all the personnel to accomplish the organization’s mission and objectives while at the same time helping them accomplish their own career objectives (French, Rayner and Rees 12-25). Staffing is fillin g and keeping filled with qualified people all the positions in the business. Some of the specific activities included in this function include recruiting, hiring, training, evaluating and compensating employees. In order to carry out this function properly a manger will liaise with the human resource department. The use of incentives has been seen as advantageous because they encourage and promote appropriate safe behavior among employees at the work place. It is a way that companies are able to demonstrate that they care for their employees and recognizes those who work safely. Secondly long term behavior can be changed through awareness and the provision of financial rewards for proper behavior and this will result in improved morale and reduced worker compensation costs. Third safety incentive programs reduce accidents at the work place as they encourage employees to work in safe conditions (Princhard). The disadvantages of safety incentive programs are that, first they do not o bligate any changes in the existing processes or procedures. Accidents are generally as a combination of some unsafe conditions and therefore by giving employees rewards they try to minimize accidents but the sane processes are still in existence. Incentives also ignore reasons such that they deflect attention from real issues and can disguise genuine deficiencies, flaws or safety management process within the organization. Third incentives are based on a wrong assumption that is unsafe acts. They assume that accidents are intentional acts and that these incentives will cause employees to stop behaving improperly which is wrong (Princhard). Maslow’s Hierarchy of Needs Maslow’s hierarchy of needs theory is a theory of motivation that is used to explain the spectrum of human behavior. He proposed that motivation is a function of five basic needs – physiological, safety, love, esteem and self-actualization. He said that these categories are arranged in a hierarchy- that human needs emerge in a predictable stair-step fashion. When one need is satisfied another need up in the ladder emerges or is activated. The process continues until the need for self-actualization is activated (Harold Koontz 290-98). Physiological needs include the following: food, water, warmth, rest and shelter. Safety needs include the